Thalassemia Unveiled: From Genetic Insights to Cutting-Edge Therapies

PROGRAM CHAIR 

Hanny Al-Samkari, MD 
Classical Hematologist and Clinical Investigator
The Peggy S. Blitz Endowed Chair in Hematology/Oncology
Massachusetts General Hospital
Associate Professor of Medicine
Harvard Medical School
Boston, MA

PROGRAM OVERVIEW 

This enduring interactive and engaging educational activity is designed to support hematologists in  advancing their knowledge and clinical skills related to the diagnosis and management of thalassemias. The  program provides exploration of the genetic and clinical characteristics associated with α- and β thalassemias, as well as a review of diagnostic standards and management of transfusion-related  complications. Participants will examine clinical evidence supporting emerging therapeutic strategies,  including pyruvate kinase activation, as well as practical approaches to incorporating novel pharmacologic  therapies into treatment.

TARGET AUDIENCE 

This activity is designed to meet the educational needs of hematologists involved in the diagnosis and  management of patients with thalassemias.

LEARNING OBJECTIVE 

Upon the completion of this program, attendees should be able to:

  • Assess the genetic and clinical characteristics of thalassemias as well as the diagnostic standards  and transfusion-related complications in managing thalassemias
  • Examine clinical evidence supporting the use of pyruvate kinase activation in treating thalassemia
  • Develop treatment strategies that incorporate new pharmacological treatments for managing patients with thalassemia

JOINT ACCREDITATION STATEMENT 

In support of improving patient care, Med Learning Group is jointly accredited by the  Accreditation Council for Continuing Medical Education (ACCME), the Accreditation  Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center  (ANCC), to provide continuing education for the healthcare team.


PHYSICIAN CREDIT DESIGNATION STATEMENT

Med Learning Group designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 CreditTM.  Physicians should claim only the credit commensurate with the extent of their participation in the enduring  activity.

NURSES (ANCC) CREDIT DESIGNATION 

Med Learning Group designates this activity for a maximum of 1.0 ANCC contact hour.

DISCLOSURE POLICY STATEMENT 

In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Integrity and Independence in Accredited Continuing Education, educational programs sponsored by Med Learning Group must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, staff, and planning committee members participating in an MLG‐sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services that are discussed in an educational activity.

DISCLOSURE OF RELEVANT FINANCIAL RELATIONSHIPS

Faculty Member Disclosures
Hanny Al-Samkari, MD Disclosures receiving consultant fees from Agios Pharmaceuticals, Inc., Amgen,  Alnylam, Argenx, Alpine, Sobi, Sanofi, Pharmacosmos, and Novartis, as well as  contracted research funding to his institution from Agios Pharmaceuticals, Inc.,  Amgen, Novartis, Vaderis, and Sobi.

All relevant financial relationships have been mitigated. 

Content Review 

The content of this activity was independently peer-reviewed by a physician and nurse reviewer.

Individuals in Control of the Content of the Activity 

The individuals in control of the content of this activity have reported the following financial relationships or  relationships to products or devices they have with ineligible companies related to the content of this CE  activity:

  • Matthew Frese, MBA, CEO of Med Learning Group, has nothing to disclose.
  • Lauren Welch, MA, Sr VP of Operations for Med Learning Group, has nothing to disclose.
  • Lauren Scott, Medical Director for Med Learning Group has nothing to disclose.
  • Tom Bregartner, MBA, VP of Outcomes and Accreditation for Med Learning Group, has nothing to disclose.
  • Daniel DaSilva, Accreditation and Outcomes Coordinator for Med Learning Group, has nothing to disclose.
  • Joan Duer-Hefele, RN, MA, CCRC, an independent nurse reviewer has nothing to disclose.
  • Arpan Patel, MD, an independent medical review, has nothing to disclose.
  • Lauren Bartunek, Program Manager for Med Learning Group, has nothing to disclose.
  • Heather Gee, Program Coordinator for Med Learning Group, has nothing to disclose.

DISCLOSURE OF UNLABELED USE 

Med Learning Group requires that faculty participating in any CE activity disclose to the audience when  discussing any unlabeled or investigational use of any commercial product or device not yet approved for  use in the United States. During this lecture, the faculty may mention the use of medications for both FDA approved and non-approved indications.

METHOD OF PARTICIPATION 

There are no fees for participating and receiving CE credit for this activity. In order to obtain your certificate  for the mentioned accreditation, participants need to successfully complete the associated pre/post  activities and evaluation. Your certificate will be provided as a downloadable file.

DISCLAIMER 

Med Learning Group makes every effort to develop CE activities that are science based. This activity is  designed for educational purposes. Participants have a responsibility to use this information to enhance  their professional development in an effort to improve patient outcomes. Conclusions drawn by the  participants should be derived from careful consideration of all available scientific information. The  participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making  expertise before applying any information, whether provided here or by others, for any professional use.

For CE questions, please contact Med Learning Group at [email protected]

Contact this CE provider at Med Learning Group for privacy and confidentiality policy statement information  at www.medlearninggroup.com/privacy-policy/

AMERICANS WITH DISABILITIES ACT 

Event staff will be glad to assist you with any special needs (eg, dietary, physical, etc). Please contact Med  Learning Group prior to participating at [email protected]

RELEASED DATE: May 15, 2025
EXPIRATION DATE: May 15, 2026

Copyright © 2025 Med Learning Group. All rights reserved. These materials may be used for personal use only. Any rebroadcast, distribution, or reuse of this presentation or any part of it in any form for other than personal use without the express written permission of Med Learning Group is prohibited.

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A Special Thank You to All HCPs

Med Learning Group sends its heartful gratitude to all healthcare professionals giving their all, 24/7, during this pandemic, despite the great risks they face. We cannot thank you enough for your courage and selfless service.

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This award is both an honor and a testament to our cumulative dedication to providing the best continuing medical education (CME) services to HCPs across the globe. We are proud to be part of this distinguished group and look forward to continuing to have MLG be one of the best CME providers in the country.

Thank you to Healthcare Business Review for this recognition and for shining a light on the importance of accurate and accessible healthcare education.

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