Precision Medicine in Action: Using Thyroid Cancer Biomarkers to Match the Right Patient with the Right Treatment at the Right Time

Please note that this program was recorded prior to the FDA approval of pralsetinib for RET-mutant medullary thyroid and RET fusion-positive thyroid cancer on December 2, 2020.

Pralsetinib is now indicated for the treatment of:

  • Adult and pediatric patients 12 years of age and older with advanced or metastatic RET-mutant medullary thyroid cancer (MTC) who require systemic therapy
  • Adult and pediatric patients 12 years of age and older with advanced or metastatic RET fusion-positive thyroid cancer who require systemic therapy and who are radioactive iodine-refractory (if radioactive iodine is appropriate)

The approvals are based on results from the phase I/II ARROW study, which demonstrated durable clinical activity in people with or without prior therapy and regardless of RET alteration genotypes.


Sylvia L. Asa, MD, PhD
Consultant in Endocrine Pathology
University Hospitals Cleveland Medical Center
And University Health Network, Toronto
Professor, Department of Pathology
Case Western Reserve University
Cleveland, OH

Lori Wirth, MD
The Elizabeth and Michael Ruane Chair of Oncology
Medical Director of Head and Neck Oncology
Massachusetts General Hospital
Associate Professor of Medicine
Harvard Medical School
Boston, MA


This case-based online activity will cover the treatment and management of patients with thyroid cancer.


This educational activity is intended for oncologists and endocrinologists as well as pathologists, along with their multidisciplinary teams in academic centers and the community setting who are especially challenged in keeping up with the most current data on new/emerging less commonly occurring genomic alterations, genomic testing methodologies, and optimal treatment decisions for patients with thyroid cancer.


  • Utilize best practices for identifying actionable thyroid cancer molecular/genomic alterations in routine clinical practice
  • Integrate available and emerging targeted treatment options into routine clinical practice for the treatment of patients with advanced thyroid cancer based on results showing actionable molecular/genomic alterations


Med Learning Group is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. This CME activity was planned and produced in accordance with the ACCME Essentials.


Med Learning Group designates this online activity for a maximum of 1.0 AMA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the online activity.


Purpose: This program would be beneficial for nurses involved in the care of patients with thyroid cancer.
CNE Credits: 1.0 ANCC Contact Hour.


Ultimate Medical Academy/CCM is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation. Awarded 1.0 contact hour of continuing nursing education of RNs and APNs.


In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support, educational programs sponsored by Med Learning Group must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, staff, and planning committee members participating in an MLG-sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturers of any commercial products and/or providers of commercial services that are discussed in an educational activity.


Sylvia Asa, MD, PhD received consulting fees from Leica Biosystems Digital Imaging Medical Advisory Board.

Lori Wirth, MD has received honorarium for advisory roles from:

  • Ayala Pharmaceuticals
  • Bayer Healthcare Pharmaceuticals (consulting fees)
  • Blueprint Medicines (consulting fees)
  • Cue BioPharma (consulting fees)
  • Cullinan Oncology
  • Eli Lilly (consulting fees)
  • Eisai (consulting fees)
  • Genentech USA
  • Merck (consulting fees)
  • Loxo Oncology (consulting fees)
  • NewLink Genetics
  • Novartis
  • Rakuten Medical
  • Honoraria received for serving on a steering committee for Eli Lilly
  • Honoraria received for serving on a data safety monitoring board for Lovance Biotherapeutics
  • CME Content Review
    The content of this activity was independently peer-reviewed.
    The reviewer of this activity has nothing to disclose.

    CNE Content Review
    The content of this activity was peer-reviewed by a nurse reviewer.
    The reviewer of this activity has nothing to disclose.

    Staff, Planners and Managers
    The staff, planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME/CE activity:
    Matthew Frese, General Manager of Med Learning Group, has nothing to disclose.
    Christina Gallo, SVP, Educational Development of Med Learning Group, has nothing to disclose.
    Ana Maria Albino, Senior Program Manager of Med Learning Group, has nothing to disclose.
    David Chatman, Medical Director of Med Learning Group, has nothing to disclose.
    Lauren Welch, MA, VP of Accreditation and Outcomes of Med Learning Group, has nothing to disclose.
    Brianna Hanson, Accreditation and Outcomes Coordinator of Med Learning Group, has nothing to disclose.


    Med Learning Group requires that faculty participating in any CME activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States.

    During this lecture, faculty may mention the use of medications for both FDA-approved and non-approved indications.


    There are no fees for participating and receiving CME/CNE credit for this enduring activity. To receive CME/CNE credit participants must:

    1. Read the CME/CNE information and faculty disclosures;
    2. Participate in the enduring activity; and
    3. Complete pre-and-post surveys and evaluation.

    You will receive your certificate as a downloadable file.


    Med Learning Group makes every effort to develop CME activities that are science-based. This activity is designed for educational purposes. Participants have a responsibility to use this information to enhance their professional development in an effort to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making before applying any information, whether provided here or by others, for any professional use.

    For CME questions, please contact Med Learning Group at [email protected].

    RELEASE DATE: December 23, 2020

    EXPIRATION DATE: December 23, 2021

    Contact this CME provider at Med Learning Group for privacy and confidentiality policy statement information at


    Staff will be glad to assist you with any special needs. Please contact Med Learning Group prior to participating at [email protected].

    Copyright © 2020 Med Learning Group. All rights reserved. These materials may be used for personal use only. Any rebroadcast, distribution, or reuse of this presentation or any part of it in any form for other than personal use without the express written permission of Med Learning Group is prohibited.

    Scroll to Top

    A Special Thank You to All HCPs

    Med Learning Group sends its heartful gratitude to all healthcare professionals giving their all, 24/7, during this pandemic, despite the great risks they face. We cannot thank you enough for your courage and selfless service.

    Connecting you with our personalized approach to continuing Medical Education

    Healthcare Business Review Award

    We are thrilled to announce that we have been recognized as one of the Top 10 Health Education Services Providers by Healthcare Business Review!

    This award is both an honor and a testament to our cumulative dedication to providing the best continuing medical education (CME) services to HCPs across the globe. We are proud to be part of this distinguished group and look forward to continuing to have MLG be one of the best CME providers in the country.

    Thank you to Healthcare Business Review for this recognition and for shining a light on the importance of accurate and accessible healthcare education.

    #TopHealthEducationProvider #MedLearningGroup #HealthcareBusinessReview #MedicalEducation

    Best of America Small Business Awards
    Best Website

    The Best of America Small Business Website award recognizes the best website launched by a small business since 2021. Technology is a key growth enabler for small businesses. The best in tech track recognizes small businesses as experts in technology and innovation from innovators, app developers, and website creators. Visit our award-winning Ophthalmology and Optometry web portal:

    The Linking Approach to Education from Gap Analysis to Outcomes

    Med Learning Group, a division of Ultimate Medical Academy, is a full-service accredited medical education company with commendation. Med Learning Group focuses on developing and implementing continuing education that improves healthcare practitioners’ ability to provide optimal care to their patients. Our goal is to provide high-quality education that is designed to deliver the highest level of outcomes for not only the practitioner, but also the patient. Med Learning Group has expertise in developing both live and online activities that are innovative, case-based, interactive and patient-centric in nature.

    Med Learning Group has expertise in developing both live and online activities that are innovative, case-based, interactive and patient-centric in nature, and we focus on applying adult learning theory and principles to our programs. Even more importantly, we understand the nuances of our target audiences and design programs with a grounded understanding of how to educate both specialty audiences and general practitioners.