Improving Outcomes for Steroid-Resistant Chronic Graft vs Host Disease: Second-Line Options and Beyond

Virtual Pathways

FACULTY

Corey S. Cutler, MD, MPH, FRCPC
Director, Adult Stem Cell Transplantation Program
Dana-Faber Cancer Institute
Professor of Medicine, Harvard Medical School
Boston, MA

PROGRAM OVERVIEW

This Virtual Pathways Online Enduring Activity takes learners on a compelling journey through second-line and beyond therapeutic options for managing steroid-resistant chronic graft-versus-host disease (SR-cGVHD), including evidence-based diagnostic criteria; clinical safety and efficacy data of recently approved and investigational therapeutic agents; and approaches to individualize treatment plans which also address the psychosocial impact of SR-cGVHD. Learn more about the mechanistic differences among the current approved therapies in the challenging second-line and beyond settings, as well as strategies to select the most effective treatment targeting disease etiopathogenesis to improve outcomes.

TARGET AUDIENCE

The intended audience for this activity is transplant specialists, oncologists, hematologists, and other healthcare professionals involved in the treatment of patients with SR-cGVHD.

LEARNING OBJECTIVES

  • Describe the etiopathogenesis of SR-cGVHD as rationale for treatment selection
  • Discuss the clinical safety and efficacy data of recently approved and investigational therapeutic agents
  • Explain optimal treatment selection and sequencing strategies based on patient-specific factors and available therapies
  • Identify strategies for managing SR-cGVHD that improve quality of life, psychosocial toxicity, and symptom burden

JOINT ACCREDITATION STATEMENT

In support of improving patient care, Med Learning Group is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.


PHYSICIAN CREDIT DESIGNATION STATEMENT

Med Learning Group designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the enduring activity.

NURSES (ANCC) CREDIT DESIGNATION

Med Learning Group designates this activity for a maximum of 1.0 ANCC contact hour.

DISCLOSURE POLICY STATEMENT

In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Integrity and Independence in Accredited Continuing Education, educational programs sponsored by Med Learning Group must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, staff, and planning committee members participating in an MLG-sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services that are discussed in an educational activity.

DISCLOSURE OF RELEVANT FINANCIAL RELATIONSHIPS

Corey S. Cutler, MD, discloses that he has received consulting fees from Syndax, Sanofi, InhibRx, Cellarity, Astellas, Rigel, Novartis, and Incyte. In addition, Dr. Cutler has ownership interests in Cimeio Therapeutics and Oxford Immune Algorithmics. Dr. Cutler serves on data and safety monitoring boards for AlloVir and Angiocrine Bioscience.
All relevant financial relationships have been mitigated.

Content Review

The content of this activity was independently peer reviewed by a physician and nurse reviewer.

Individuals in Control of the Content of the Activity

The individuals in control of the content of this activity have reported the following financial relationships or relationships to products or devices they have with ineligible companies related to the content of this CME/CE activity:

  • Matthew Frese, General Manager of Med Learning Group, has nothing to disclose.
  • Christina Gallo, SVP, Educational Development of Med Learning Group, has nothing to disclose.
  • Anita Misra-Press, PhD, Medical Director of Med Learning Group, has nothing to disclose.
  • Shannon Mutch MS, RN, OCN, has nothing to disclose.
  • Michael Milano, MD, has nothing to disclose.
  • A medical reviewer from CME Peer Review LLC, has nothing to disclose.
  • Ana Maria Albino, Senior Program Manager of Med Learning Group, has nothing to disclose.
  • Jessica Feygin, Associate Program Manager of Med Learning Group, has nothing to disclose.
  • Lauren Welch, MA, VP of Accreditation and Outcomes of Med Learning Group, has nothing to disclose.
  • Daniel Dasilva, Accreditation and Outcomes Coordinator of Med Learning Group, has nothing to disclose.

DISCLOSURE OF UNLABELED USE

Med Learning Group requires that faculty participating in any CE activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States. During this lecture, the faculty may mention the use of medications for both FDA-approved and non-approved indications.

METHOD OF PARTICIPATION

There are no fees for participating and receiving CE credit for this activity. In order to obtain your certificate for the mentioned accreditation, participants need to successfully complete the associated pre/post activities and evaluation. Your certificate will be provided as a downloadable file.

DISCLAIMER

Med Learning Group makes every effort to develop CE activities that are science based. This activity is designed for educational purposes. Participants have a responsibility to use this information to enhance their professional development in an effort to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making expertise before applying any information, whether provided here or by others, for any professional use.

For CE questions, please contact Med Learning Group at [email protected]

Contact this CE provider at Med Learning Group for privacy and confidentiality policy statement information at www.medlearninggroup.com/privacy-policy/

AMERICANS WITH DISABILITIES ACT

Event staff will be glad to assist you with any special needs. Please contact Med Learning Group prior to participating at [email protected]

RELEASED DATE: April 08, 2024
EXPIRATION DATE: April 08, 2025

Copyright ©2024 Med Learning Group. All rights reserved. These materials may be used for personal use only. Any rebroadcast, distribution, or reuse of this presentation or any part of it in any form for other than personal use without the express written permission of Med Learning Group is prohibited.

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