Getting to the Heart of Diabetes: The Role of GLP-1 Receptor Agonists in Reducing Cardiovascular Risk


Richard E. Pratley, MD
Samuel E. Crockett Chair in Diabetes Research
Medical Director
AdventHealth Diabetes Institute
Senior Investigator and Diabetes Program Lead
AdventHealth Translational Research Institute
Adjunct Professor of Medicine
Johns Hopkins University School of Medicine

Darren K. McGuire, MD, MHSC
Distinguished Teaching Professor of Medicine
Division of Cardiology
Dallas Heart Ball Chair for Research on Heart Disease in Women
University of Texas Southwestern Medical Center
Lead Physician
Parkland Hospital and Health System Cardiology Clinics


This case-based activity will cover the long-term treatment, management, and improvement of cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM).


This educational activity is intended for cardiology healthcare professionals.


  • Select patients with T2DM who would benefit from the CV effects of GLP-1 RAs
  • Apply guidelines and recent clinical data to the choice of GLP-1 receptor agonists for reducing CV risk in patients with T2DM
  • Analyze the clinical implications of results from Cardiovascular Outcomes Trials of GLP-1 receptor agonists and emerging incretin-based therapies
  • Implement practical strategies for initiating and administering GLP-1 receptor agonists (including device training, dosing and escalation, follow-up care and adjustment of other medications)


Med Learning Group is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

This CME activity was planned and produced in accordance with the ACCME Essentials.


Med Learning Group designates this activity for a maximum of 1.5 AMA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Purpose: This program would be beneficial for nurses involved in the long-term treatment, management, and improvement of CV outcomes in patients with T2DM.
CNE Credits: 1.5 ANCC Contact Hour(s).


Ultimate Medical Academy/CCM is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation. Awarded 1.5 contact hours of continuing nursing education of RNs and APNs.


This program has received prior approval with the Commission on Dietetic Registration for dietitians and RDs.


In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support, educational programs sponsored by Med Learning Group must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, staff, and planning committee members participating in an MLG-sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturers of any commercial products and/or providers of commercial services that are discussed in an educational activity.


Richard Pratley, MD reports research grants and consulting and/or speaker’s fees from Hanmi Pharmaceutical Co, Janssen, MSD, Merck, Novo Nordisk, Pfizer Inc, Poxel SA, Sanofi, Scohia Pharma Inc., and Sun Pharmaceutical Industries. All honoraria are directed toward AdventHealth, a non-profit organization supporting education and research.

He has contracted research for Lexicon Pharmaceuticals, Hanmi Pharmaceuticals Co., Ligand Pharmaceuticals, Lilly, Merck, Novo Nordisk, Poxel SA and Sanofi. All grant fund payments were made directly to AdventHealth, a nonprofit organization.

Darren K. McGuire, MD, MHSc reports clinical trials leadership for Merck & Co, Pfizer, AstraZeneca, Janssen, Lilly USA, Boehringer Ingelheim, Novo Nordisk, Lexicon, Eisai, GlaxoSmithKline, Sanofi, Esperion, and CSL Behring. He consults for Novo Nordisk, Sanofi, Boehringer Ingelheim, Lilly USA, Merck & Co.; AstraZeneca, Metavant Sciences, Applied Therapeutics, and Afimmune.

CME Content Review
The content of this activity was independently peer-reviewed.
The reviewer of this activity has nothing to disclose.

CNE Content Review
The content of this activity was peer-reviewed by a nurse reviewer.
The reviewer of this activity has nothing to disclose.

The staff, planners, and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME/CE activity:
Matthew Frese, General Manager of Med Learning Group has nothing to disclose.
Christina Gallo, SVP, Educational Development of Med Learning Group has nothing to disclose.
Ashley Whitehurst, Program Manager of Med Learning Group has nothing to disclose.
Cindy Lampner, Medical Director of Med Learning Group has nothing to disclose.
Lauren Welch, MA, VP of Accreditation and Outcomes of Med Learning Group has nothing to disclose.
Russie Allen, Accreditation and Outcomes Coordinator of Med Learning Group has nothing to disclose.


Med Learning Group requires that faculty participating in any CME activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States.

During this lecture, faculty may mention the use of medications for both FDA-approved and non-approved indications.


There are no fees for participating and receiving CME credit for this activity. To receive CME/CNE/CDR credit participants must:

  1. Read the CME/CNE information and faculty disclosures;
  2. Participate in the enduring activity; and
  3. Complete pre-and-post surveys and evaluation.

You will receive your certificate as a downloadable file.


Med Learning Group makes every effort to develop CME activities that are science-based. This activity is designed for educational purposes. Participants have a responsibility to use this information to enhance their professional development in an effort to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making before applying any information, whether provided here or by others, for any professional use.

For CME questions, please contact Med Learning Group at [email protected].

RELEASE DATE: November 30, 2020

EXPIRATION DATE: November 30, 2021

Contact this CME provider at Med Learning Group for privacy and confidentiality policy statement information at


Staff will be glad to assist you with any special needs. Please contact Med Learning Group at [email protected].

Copyright © 2020 Med Learning Group. All rights reserved. These materials may be used for personal use only. Any rebroadcast, distribution, or reuse of this presentation or any part of it in any form for other than personal use without the express written permission of Med Learning Group is prohibited.

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