Developing Immunotherapy for Advanced Disease: Leveraging the Tumorigenesis of Basal Cell Skin Cancer – A Whiteboard View

FACULTY

David M. Miller, MD, PhD, FAAD
Director, Center for Merkel Cell Carcinoma
Co-Director, NMSC Multi-Disciplinary Clinic
Division of Hematology/Oncology and Department of Dermatology
Massachusetts General Hospital
Boston, MA

Emily S. Ruiz, MD, MPH
Academic Director, Mohs and Dermatologic Surgery Center
Director, High-Risk Skin Cancer Clinic,
Dana-Farber/Brigham and Women’s Cancer Center
Assistant Professor, Harvard Medical School
Boston, MA


PROGRAM OVERVIEW

This case-based activity will cover the treatment and management of patients with advanced/metastatic basal cell carcinoma.


LEARNING OBJECTIVES

  • Review the roles of both aberrant pathways and immune dysfunction in the pathogenesis of BCC
  • Describe grading, staging, biopsy techniques, and treatment of basal cell carcinoma from low to high risk
  • Apply the AAD practice guidelines for a multi-disciplinary approach to treatment of locally advanced and metastatic BCC
  • Discuss late-stage immunotherapy trial data in the treatment of patients with advanced or metastatic basal cell skin cancer

TARGET AUDIENCE

This activity is designed to meet the educational needs of primarily dermatologists, onco-dermatologists, and medical oncologists, Mohs surgeons, and other healthcare practitioners who care for patients with advanced/metastatic basal cell skin cancer.


ACCREDITATION STATEMENT

Med Learning Group is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.


CREDIT DESIGNATION STATEMENT

Med Learning Group designates this enduring activity for a maximum of 1.25 AMA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the enduring activity.


NURSING CREDIT INFORMATION

Purpose: This program would be beneficial for nurses involved in the care of patients with basal cell skin cancer.
Credits: 1.25 ANCC Contact Hours


CNE ACCREDITATION STATEMENT

Ultimate Medical Academy/Complete Conference Management (CCM) is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation. Awarded 1.25 contact hours of continuing nursing education of RNs and APNs.


DISCLOSURE POLICY STATEMENT

In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support, educational programs sponsored by Med Learning Group must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, staff, and planning committee members participating in a MLG-sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services that are discussed in an educational activity.


DISCLOSURE OF FINANCIAL RELATIONSHIPS

Dr. Miller is a stockholder of Checkpoint Therapeutics. He is also a consultant for Checkpoint Therapeutics, EMD Serono, Merck, Pfizer, Regeneron and Sanofi Genzyme. Additionally, he has contracted research for Regeneron, Kartos, Incyte, and NeoImmuneTech, Inc.

Dr. Ruiz is a PI on the cemiplimab BCC trial, co-I on other Regeneron trials, and co-I on a Merck trial. She also receives consulting fees from Regeneron/Sanofi and Genentech.

The independent reviewers, staff, planners, and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests:

CME Content Review
The content of this activity was independently peer reviewed.
The reviewer of this activity has nothing to disclose.

CNE Content Review
The content of this activity was peer reviewed by a nurse reviewer.
The reviewer of this activity has nothing to disclose.

Staff, Planners, and Managers
The staff, planners, and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME/CE activity:

Matthew Frese, General Manager of Med Learning Group has nothing to disclose.
Christina Gallo, SVP, Educational Development for Med Learning Group has nothing to disclose.
Lauren Welch, MA, VP, Outcomes and Accreditation for Med Learning Group has nothing to disclose.
Brianna Hanson, Outcomes Coordinator for Med Learning Group has nothing to disclose.
Chris Drury, MA, MS, MBA, Scientific and Medical Services for Med Learning Group has nothing to disclose.
Melissa A. Johnson, Senior Program Manager for Med Learning Group has nothing to disclose.


DISCLOSURE OF UNLABELED USE

Med Learning Group requires that faculty participating in any CME activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States.

During the course of this lecture, the faculty may mention the use of medications for both FDA-approved and non-approved indications.


METHOD OF PARTICIPATION

There are no fees for participating and receiving CME/CNE credit for this web-based enduring activity. To receive CME/CNE credit participants must:

  1. Read the CME/CNE information and faculty disclosures.
  2. Participate in the enduring activity.
  3. Complete and submit the evaluation form to Med Learning Group.

You will receive your certificate as a downloadable file.


DISCLAIMER

Med Learning Group makes every effort to develop CME activities that are scientifically based. This activity is designed for educational purposes. Participants have a responsibility to utilize this information to enhance their professional development in an effort to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making before applying any information, whether provided here or by others, for any professional use.

AMERICANS WITH DISABILITIES ACT

Event staff will be glad to assist you with any special needs. Please contact Med Learning Group prior to the enduring event at info@medlearninggroup.com.

For CME questions, please contact Med Learning Group at info@medlearninggroup.com.

RELEASE DATE: February 25, 2021

EXPIRATION DATE: February 25, 2022

Contact this CME provider at Med Learning Group for privacy and confidentiality policy statement information at www.medlearninggroup.com/privacy-policy/

Copyright © 2021 Med Learning Group. All rights reserved. These materials may be used for personal use only. Any rebroadcast, distribution, or reuse of this presentation or any part of it in any form for other than personal use without the express written permission of Med Learning Group is prohibited.

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