A 3-D View of Novel Targeted Agents in Metastatic, Hormone-Receptor Positive, HER-2 Negative Breast Cancer

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Sara Hurvitz, MD
Assistant Clinical Professor of Medicine
University of California, Los Angeles (UCLA)
Co-Director of the Santa Monica-UCLA Outpatient Oncology Practice
Medical Director, Clinical Research Unit, Jonsson Comprehensive Cancer Center
Santa Monica, California


Jennifer Diamond, MD
Medical Director, Cancer Clinical Trials Office (CCTO)
University of Colorado Cancer Center
Co-Director, Women’s Cancer Developmental Therapeutics (WCDT) Program
Associate Professor of Medicine
Division of Medical Oncology, DT and Breast Cancer Programs
University of Colorado Anschutz Medical Campus
Aurora, CO


This live activity will cover the treatment and management of patients with Metastatic, Hormone-Receptor Positive, HER-2 Negative Breast Cancer.


This CME initiative is designed to meet the educational needs of medical oncologists, surgeons, ONS nurses, and other health care providers involved in the treatment of patients with breast cancer.


On completing the program, attendees should be able to:

  • Describe the genetic alterations in cellular pathways that control cell cycle transition in hormone receptor-positive breast cancer
  • Review the pharmacodynamics and pharmacokinetics of the CDK 4/6 inhibitors in hormone receptor-positive breast cancer
  • Discuss the CDK 4/6 inhibitor clinical trial data for patients with HR positive, HER-2 negative advanced or metastatic breast cancer
  • Explain the monitoring of and practical side effect management strategies for CDK 4/6 inhibitors


Med Learning Group is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.


Med Learning Group designates this enduring activity for a maximum of 1.0 AMA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


This program would be beneficial for nurses involved in the treatment and management of patients with breast cancer.

CNE Credits:
1.0 ANCC Contact Hour

CNE Accreditation Statement:
Ultimate Medical Academy/CCM is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation. Awarded 1.0 contact hour of continuing nursing education of RNs and APNs.


In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support, educational programs sponsored by Med Learning Group must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, staff, and planning committee members participating in a MLG-sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services that are discussed in an educational activity.


Dr. Hurvitz’s receives funding (paid to UCLA) for contracted research from Amgen, Bayer, BI Pharma, Genentech, GSK, Lilly, Novartis, Pfizer, Roche, PUMA, Merrimack, Medivation, Dignitana, DBI Pharma, Bomarin, Cascadian, and Seattle Genetics. She has traveled for Lilly, Novartis, OBI Pharma, and Bayer.

Dr. Jennifer Diamond, reports that she has no relevant relationships with a commercial entity or

CME Content Review
The content of this activity was independently peer reviewed.
The reviewer of this activity has nothing to disclose.

CNE Content Review
The content of this activity was independently peer reviewed.
The reviewer of this activity has nothing to disclose.

The staff, planners, and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME/CE activity:
Matthew Frese, MBA, General Manager of Med Learning Group, has nothing to disclose.
Christina Gallo, SVP, Educational Development for Med Learning Group, has nothing to disclose.
Sharine Griggs, Program Manager for Med Learning Group, has nothing to disclose.
Flavia Piazza, PhD, VP Scientific and Medical Services for Med Learning Group, has nothing to disclose.
Lauren Welch, MA, VP, Accreditation and Outcomes, has nothing to disclose.


Med Learning Group requires that faculty participating in any CME activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States.
During this lecture, the faculty may mention the use of medications for both FDA-approved and nonapproved indications.

There are no fees for participating and receiving CME credit for this enduring activity. To receive CME/CNE credit participants must:

1. Read the CME/CNE information and faculty disclosures;
2. Participate in the live activity.
3. Submit the evaluation form to Med Learning Group.


Med Learning Group makes every effort to develop CME activities that are science-based.
This activity is designed for educational purposes. Participants have a responsibility to use this information to enhance their professional development in an effort to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making before applying any information, whether provided here or by others, for any professional use.

For CME questions, please contact: Med Learning Group at info@medlearninggroup.com.

Contact this CME provider at Med Learning Group for privacy and confidentiality policy statement information at: http://www.medlearninggroup.com/privacy-policy/


Event staff will be glad to assist you with any special needs (eg, physical, dietary, etc.). Please contact Med Learning Group prior to the enduring event at info@medlearninggroup.com

RELEASE DATE: May 17, 2018


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Participation Statement
This educational activity provides training necessary for licensed attendees to maintain state licensing requirements. The tuition for this educational activity is subsidized in part by unrestricted educational grants, including for those attendees who have successfully completed the state licensing requirements for their respective fields. This subsidy is reflected in the registration fees for this activity.

Copyright © 2018 Med Learning Group. All rights reserved. These materials may be used for personal use only. Any rebroadcast, distribution, or reuse of this presentation or any part of it in any form for other than personal use without the express written permission of Med Learning Group is prohibited.