The Promise of a Changing Landscape in the Management of Advanced Hepatocellular Carcinoma: The Role of Immunotherapy

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Robert G. Gish, MD
Robert G. Gish Consultants LLC
Professor Consultant
Stanford University
Stanford, CA


Thomas Cartwright, MD
Co-Chairman of the US Oncology GI Research
Associate Professor of Medicine
University of Central Florida College of Medicine
Ocala, FL


This live activity will cover the treatment and management of patients with hepatocellular carcinoma (HCC) and liver diseases.


This activity is intended for oncologists, hepatologists, gastroenterologists, and health care professionals who manage patients with liver cancer and liver diseases.


Upon completion of the program, attendees should be able to:

  • Describe current immunotherapy agents’ mechanisms of action and their effects on tumorigenic immune pathways in HCC
  • Discuss the current systemic targeted treatment options for patients with advanced HCC
  • Review the current clinical trial data for emerging immunotherapeutic compounds to advance the knowledge of their efficacy, safety, and appropriate use in patients with advanced HCC
  • Recognize and improve management of the unique immune-related adverse events associated with immunotherapy in the treatment of hepatocellular carcinoma


Med Learning Group is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.


Med Learning Group designates this enduring activity for a maximum of 1.0 AMA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


This program would be beneficial for nurses involved in the treatment and management of patients with liver cancer and liver diseases.

CNE Credits:
1.0 ANCC Contact Hour

CNE Accreditation Statement:
Ultimate Medical Academy/CCM is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation. Awarded 1.0 contact hour of continuing nursing education of RNs and APNs.


In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support, educational programs sponsored by Med Learning Group must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, staff, and planning committee members participating in a MLG-sponsored activity are required to disclose any relevant financial interests or other relationships with the manufacturers of any commercial products and/or providers of commercial services that are discussed in an educational activity.


Dr. Gish has served on clinical trials for eStudySite Advisor; has chaired a clinical advisory board for Arrowhead, and has served as an advisory consultant for the following diagnostic companies: Biocollections, Prometheus, Quest, and Theranos. He has also been on the Data Safety Monitoring Board for Ionis.

Dr Gish has a speaker’s contract to present promotional talks for Bayer, BMS, Gilead Sciences Inc., Salix/Valeant, AbbVie, Merck.

He is also minor stock shareholder of Athenex, Triact, Synageva, RiboSciences, and CoCrystal and holds stock options at Arrowhead and Eiger.

Dr. Cartwright has served on speakers’ bureau for Amgen and Taiho. He is a consultant for Taiho, Genentech, and Lilly and received research funding for Bayer.

CME Content Review
The content of this activity was independently peer reviewed.
The reviewer of this activity has nothing to disclose.

CNE Content Review
Nurse Reviewer: Lynnsey Grzybowski, RN, has no relevant financial relationships to disclose.

The staff, planners, and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME/CE activity:

Matthew Frese, MBA, General Manager of Med Learning Group, has nothing to disclose.
Christina Gallo, SVP, Educational Development for Med Learning Group, has nothing to disclose.
Sharine Griggs, Program Manager for Med Learning Group, has nothing to disclose.
Chris Drury, PhD, Medical Services for Med Learning Group, has nothing to disclose.
Lauren Welch, MA, VP, Accreditation and Outcomes, has nothing to disclose.


Med Learning Group requires that faculty participating in any CME activity disclose to the audience discussion of any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States.
During this lecture, the faculty may mention the use of medications for both FDA-approved and nonapproved indications.

There are no fees for participating and receiving CME credit for this enduring activity. To receive CME/CNE credit participants must:

1. Read the CME/CNE information and faculty disclosures;
2. Participate in the enduring activity;
3. Complete pre-and-post surveys; and
4. Submit the evaluation form to the Med Learning Group.

You will receive your certificate via email within 30 days.


Med Learning Group makes every effort to develop CME activities that are science-based.

This activity is designed for educational purposes. Participants have a responsibility to use this information to enhance their professional development in an effort to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making before applying any information, whether provided here or by others, for any professional use.

For CME questions, please contact: Med Learning Group at

Contact this CME provider at Med Learning Group for privacy and confidentiality policy statement information at:


Event staff will be glad to assist you with any special needs (eg, physical, dietary, etc.). Please contact Med Learning Group prior to the enduring event at

RELEASE DATE: February 6, 2018

EXPIRATION DATE: February 6, 2019

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Participation Statement
This educational activity provides training necessary for licensed attendees to maintain state licensing requirements. The tuition for this educational activity is subsidized in part by unrestricted educational grants, including for those attendees who have successfully completed the state licensing requirements for their respective fields. This subsidy is reflected in the registration fees for this activity.

Copyright © 2018 Med Learning Group. All rights reserved. These materials may be used for personal use only. Any rebroadcast, distribution, or reuse of this presentation or any part of it in any form for other than personal use without the express written permission of Med Learning Group is prohibited.