The Evolution of Maintenance Therapy in Advanced Non-Small Cell Lung Carcinoma: A Patient Simulation

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Mark A. Socinski, MD
Professor of Medicine and Thoracic Surgery
Director, Lung Cancer Section, Division of Hematology Oncology
Co-Director, UPMC Lung Cancer Center of Excellence
Co-Director, Lung and Thoracic Malignancies Program
University of Pittsburgh, UPMC Cancer Pavilion
Pittsburgh, PA


This activity will focus on healthcare practitioners and their decision-making process regarding treatment and management of patients with NSCLC.


This activity is designed to meet the educational needs of oncologists, oncology nurses, pathologists, radiologists, and other healthcare practitioners who care for patients with lung cancer.


After completing the CME activity, learners should be better able to:

  • Review guidelines recommending histological subtypes and gene signatures useful in the selection of individualized therapy for each patient with advanced NSCLC
  • Describe the evidence supporting the relationship between NSCLC patient overall survival/quality of life and current evidence-based cancer maintenance therapy options
  • Assess clinical trial evidence for and against switching therapeutic strategies and maintenance regimens across all lines of therapy in clinical practice
  • Interpret clinical data from studies of new targeted agents and their combinations, as well as those in development, with an emphasis on approaches to treatment-resistant or difficult-to-treat patients with advanced NSCLC


Med Learning Group is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.


Med Learning Group designates this enduring activity for a maximum of 0.5 AMA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the enduring activity.


UMA/Complete Conference Management is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s COA. Complete Conference Management will provide this educational activity for 0.5 contact hours.


In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support, educational programs sponsored by Med Learning Group must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, staff, and planning committee members participating in a MLG-sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services that are discussed in an educational activity.


Mark Socinski, MD, has received funding to serve as a speaker for BMS, Genentech and Lilly and has received research support from BMS, Genentech and Pfizer.

CME Content Review
The content of this activity was independently peer reviewed.
The reviewer of this activity has nothing to disclose.

CNE Content Review
The content of this activity was peer reviewed by a nurse reviewer and the reviewer of this activity has nothing to disclose.

Planning Committee
The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

Matthew Frese, MBA, General Manager of Med Learning Group, has nothing to disclose.
Christina Gallo, SVP, Educational Development for Med Learning Group, has nothing to disclose.
Ana Maria Albino, Program Manager for Med Learning Group, has nothing to disclose.
Nina Oshiokpekhai, MS, PharmD, Medical Director for Med Learning Group, has nothing to disclose.
Lauren Welch, MA, VP, Accreditation and Outcomes for Med Learning Group, has nothing to disclose.


Med Learning Group requires that faculty participating in any CME activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States.
During the course of this lecture, the faculty may mention the use of medications for both FDA-approved and non-approved indications.


  • Read the learning objectives and faculty disclosures.
  • Participate in the activity.
  • Complete the post-test and activity evaluation.
  • Physicians who successfully complete the post-test and evaluation will receive CME credit.
  • You must score 70% or higher on the post-test to receive credit for this activity.
  • All other participants who successfully complete the post-test and evaluation will receive a certificate of participation.


Med Learning Group makes every effort to develop CME activities that are scientifically based. This activity is designed for educational purposes. Participants have a responsibility to utilize this information to enhance their professional development in an effort to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making before applying any information, whether provided here or by others, for any professional use.

For CME questions, please contact: Med Learning Group at

Contact this CME provider at Med Learning Group for privacy and confidentiality policy statement information at:

RELEASE DATE: March 28, 2018

EXPIRATION DATE: March 28, 2019

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Participation Statement
This educational activity provides training necessary for licensed attendees to maintain state licensing requirements. The tuition for this educational activity is subsidized in part by unrestricted educational grants, including for those attendees who have successfully completed the state licensing requirements for their respective fields. This subsidy is reflected in the registration fees for this activity.

Copyright © 2018 Med Learning Group. All rights reserved. These materials may be used for personal use only. Any rebroadcast, distribution, or reuse of this presentation or any part of it in any form for other than personal use without the express written permission of Med Learning Group is prohibited.